Seed AI & Technology Funders

AlphaLab is a nationally recognized startup accelerator based in Pittsburgh, supporting early-stage companies across software, hardware, life sciences, and robotics. Founded in 2008 and powered by Innovation Works, AlphaLab provides founders with capital, mentorship, and a structured program to accelerate growth. The platform operates multiple specialized tracks, including AlphaLab (software), AlphaLab Gear (hardware), AlphaLab Health (life sciences), and Robotics Factory, offering tailored support depending on the company’s sector. AlphaLab has played a key role in building Pittsburgh into a leading innovation hub, helping startups move from idea to scalable venture.

Angelini Ventures is the venture capital arm of Angelini Industries, investing in innovative startups across biotech and digital health. The firm focuses on advancing healthcare through breakthrough therapies, medical technologies, and data-driven solutions. With a global investment strategy, Angelini Ventures backs early and growth-stage companies working to improve patient outcomes and transform how diseases are treated and managed. The firm combines capital with deep industry expertise and strategic support from its parent organization.

Avaana Capital is an India-based venture capital firm investing in climate and sustainability solutions across sectors such as energy, mobility, agriculture, and industrial systems. The firm backs early-stage founders building scalable technologies that address climate change while driving economic growth. Co-founded by Anjali Bansal, Avaana combines deep operational expertise with a strong network across government, corporates, and global investors. The firm focuses on enabling the transition to a low-carbon economy through innovation and technology.

Climate Collective is a leading innovation network that specializes in putting digital technologies to work for climate and nature at scale. They focus on connecting AI and digital tools with environmental impact, running innovation programs and building AI fluency across climate and nature nonprofits. The organization operates by connecting innovators, nonprofits, and global leaders to turn technology into lasting climate and nature impact. They accomplish this through running innovation programs, building AI fluency across climate and nature organizations, and convening sustainability leaders and technologists to foster collaboration and knowledge sharing. Climate Collective plays a crucial role in the ecosystem by bridging the gap between technology innovation and environmental impact. Their flagship AI Explorers Summit brings together 100 leaders annually and is co-hosted by major organizations like Conservation International, UNDP, and TechChange, demonstrating their significant influence in shaping how AI is responsibly deployed for climate and nature solutions.

Oncology Ventures is a healthcare-focused venture capital firm investing in commercially validated startups transforming cancer care through data, technology, artificial intelligence, and healthcare infrastructure innovation. Founded by cancer survivor Ben Freeberg, the firm focuses on solving systemic challenges across the oncology ecosystem, from early detection and diagnostics to patient navigation, care delivery, and survivorship. The firm backs companies building the non-drug infrastructure of cancer care, helping improve outcomes, reduce inefficiencies, and increase access to evidence-based treatment for patients across the healthcare system.

Pay it Forward Ventures (PIF) builds better lives for billions by investing in source-solving rather than symptom-solving. They fund and found ventures that create new paradigms across financial technology, health, energy, and digital infrastructure — and donate 20% of GP profits to philanthropy because they believe in paying it forward.

Praxis is a global venture-building ecosystem supporting entrepreneurs, nonprofits, investors, and culture makers motivated by faith to address major social and cultural challenges. Through accelerators, fellowships, mentorship, and community-building programs, Praxis helps founders build “redemptive ventures” focused on renewal, restoration, and long-term societal impact. The organization supports both for-profit and nonprofit ventures across sectors including education, healthcare, technology, community development, social innovation, and ethical entrepreneurship.

ReGen Ventures is an impact-focused venture capital firm that invests in foundational regenerative technologies designed to power a future of abundance. They focus on four core investment areas: clean energy, planetary intelligence, programmable matter, and adaptive robotics, partnering with founders who are building transformative technologies from the atomic to planetary scale. The firm operates with a mission to reimagine the world by supporting technologies that make regeneration inevitable, enabling infinite growth and prosperity on a finite planet. They take a hands-on approach with founders, providing comprehensive support that ranges from business modeling to personal wellness, emphasizing long-term sustainable returns over short-term wins. ReGen Ventures positions itself as an innovator in the investment space, paving a new path for what investments should be by focusing on root causes rather than symptoms of environmental challenges. They are building what they call a "ReGenerative Future" where climate change is reframed as an opportunity for transformation, backing founders with unreasonable ambition who alter understanding of what's possible in addressing planetary challenges.

The Rockefeller Foundation is one of the world’s largest and most influential philanthropic organizations, focused on advancing human well-being through large-scale investments in energy access, food systems, health, economic opportunity, climate resilience, and emerging technologies. Founded in 1913, the foundation partners with governments, nonprofits, corporations, and local communities to tackle systemic global challenges through innovative finance, data, and technology-driven solutions. The foundation is known for making ambitious “big bets” aimed at improving the lives of hundreds of millions of people worldwide, particularly in underserved and economically vulnerable communities.

SOSV is a global venture capital firm and accelerator founded in 1995, operating one of the most active deep tech and life sciences investment programs in the world. The firm runs multiple accelerator programs, including HAX for hardware and robotics, IndieBio for life sciences and biotech, and Orbit for climate and sustainability — providing intensive company-building support alongside early-stage capital. With over $1.5 billion in AUM and a portfolio exceeding 1,000 companies across more than 70 countries, SOSV occupies a distinctive position in the venture landscape: a programmatic investor that takes companies from idea stage through to growth and beyond. The firm's accelerator model means it is often the first institutional check into a company, with follow-on capability through later rounds. SOSV has a strong impact orientation across its portfolio, with climate, food systems, health, and sustainability representing a significant share of its investments. Its programs in particular have become known as launchpads for companies working on hard scientific and engineering problems that require more than capital to succeed.

The UNICEF Venture Fund is UNICEF’s innovation investment vehicle that provides equity-free funding and support to early-stage frontier technology startups in emerging markets. The fund invests in open source solutions that have the potential to improve outcomes for children and young people globally. Focused on technologies such as artificial intelligence, blockchain, climate technology, digital public infrastructure, data systems, and emerging technologies, the fund backs entrepreneurs building scalable solutions in countries where UNICEF operates. Beyond funding, portfolio companies receive mentorship, technical assistance, and access to UNICEF’s global network of partners, experts, and country offices. A core differentiator of the UNICEF Venture Fund is its commitment to open source technology and Digital Public Goods, ensuring that innovations can be adapted, reused, and scaled to benefit communities worldwide. Since launching, the fund has supported startups across Africa, Asia, Latin America, Eastern Europe, and other emerging technology ecosystems.